Cart
sales@molnova.com
Home - Products - Membrane Transporter/Ion Channel - NMDAR - Lanicemine dihydrochloride

Lanicemine dihydrochloride

CAS No. 153322-06-6

Lanicemine dihydrochloride( —— )

Catalog No. M35423 CAS No. 153322-06-6

Lanicemine dihydrochloride (AZD-6765 dihydrochloride) is a low-capture NMDA channel blocker with antidepressant activity and can be used to study neurological diseases.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
5MG 46 Get Quote
10MG 81 Get Quote
25MG 165 Get Quote
50MG 273 Get Quote
100MG 410 Get Quote
500MG 888 Get Quote
1G Get Quote Get Quote
Get Quotation Bulk Inquiry Add to Cart

Biological Information

  • Product Name
    Lanicemine dihydrochloride
  • Note
    Research use only, not for human use.
  • Brief Description
    Lanicemine dihydrochloride (AZD-6765 dihydrochloride) is a low-capture NMDA channel blocker with antidepressant activity and can be used to study neurological diseases.
  • Description
    Lanicemine (AZD6765) dihydrochloride is a low-trapping NMDA channel blocker (Ki of 0.56-2.1 μM for NMDA receptor; IC50s of 4-7 μM and 6.4 μM in CHO and Xenopus oocyte cells, respectively). Antidepressant effects.
  • In Vitro
    ——
  • In Vivo
    Animal Model:Male Sprague-Dawley ratsDosage:3, 10 or 30?mg/kg Administration:Intraperitoneal Result:Produced pronounced dose-dependent elevations in spontaneous gamma-band EEG, but only gamma changes for Ketamine were tightly coupled to increases in locomotor activity.
  • Synonyms
    ——
  • Pathway
    Membrane Transporter/Ion Channel
  • Target
    NMDAR
  • Recptor
    NMDAR
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    153322-06-6
  • Formula Weight
    271.19
  • Molecular Formula
    C13H16Cl2N2
  • Purity
    >98% (HPLC)
  • Solubility
    In Vitro:?DMSO : 240 mg/mL (884.99 mM; Ultrasonic )H2O : ≥ 100 mg/mL (368.75 mM)
  • SMILES
    N[C@H](C1=CC=CC=C1)CC2=CC=CC=N2.Cl.Cl
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Sanacora G, et al. Lanicemine: a low-trapping NMDA channel blocker produces sustained antidepressant efficacywith minimal psychotomimetic adverse effects. Mol Psychiatry. 2014 Sep;19(9):978-85.?
Calculator

Molecular Weight Calculator

Dilution Calculator

Molarity Calculator

molnova catalog
related products

  • SDZ 220-040

    SDZ 220-040 is a selective mammalian NMDA receptor antagonist that induces a partially gravity-free mode of root growth.

  • 5,7-Dichlorokynureni...

    5,7-Dichlorokynurenic acid is an NMDA receptor antagonist.

  • MRZ 2-514

    MRZ 2-514 is a strychnine-insensitive modulatory site of the NMDA receptor (glycineB)antagonist with Ki of 33 μM.

Sign In Join Free